Sam68 regulation of alternative splicing in the developing cerebellum

ABSTRACT: We uncover a Sam68-dependent splicing program during cerebellar development. These events direct proper isoform expression of the genes required to guarantee the establishment of the correct spatial/temporal neural circuitry. The dysregulation in Sam68 null mice leads to functional defects in adult neurons

ORGANISM(S): Mus musculus

PROVIDER: GSE133711 | GEO | 2020/06/01

REPOSITORIES: GEO