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Stem cells utilize m6A-mediated decay via YTHDF2 to regulate neural differentiation and promote pluripotency

ABSTRACT: The m6A methylation pathway has previously been shown to influence pluripotency. YTHDF2 is an RNA binding protein that interacts with m6A-modified RNAs to facilitate their degradation. We sought to identify the cohort of RNAs targeted by YTHDF2 in human induced pluripotent stem cells (iPSC).

ORGANISM(S): Homo sapiens

PROVIDER: GSE133898 | GEO | 2020/03/21

REPOSITORIES: GEO

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Stem cells utilize m6A-mediated decay via YTHDF2 to regulate neural differentiation and promote pluripotency

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