Genomics

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Genome-wide DNA demethylation of HML58-3 (a derivative cell line of HCT116) after treatment of DAC, OR-2003, and OR-2100


ABSTRACT: A derivative cell line of HCT116, HML58-3, was established to detect DNA demethylating agents [Okochi-Takada E, Epigenetics. 2018;13:147-55.]. HML58-3 cells were treated with DNA demethylating agents (DAC, OR-2003, and OR-2100). Genome-wide DNA methylation was analyzed using the Infinium Human MethylationEPIC BeadChip. Overall design: Bisulfite converted DNA from the 4 samples were hybridized to the Infinium Human MethylationEPIC BeadChip.

INSTRUMENT(S): Infinium MethylationEPIC

ORGANISM(S): Homo sapiens  

SUBMITTER: Naoko Hattori  

PROVIDER: GSE134293 | GEO | 2019-08-01

REPOSITORIES: GEO

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