Single-cell analysis of gene expression variation and phenotype switching in melanoma

ABSTRACT: We combine extensive profiling of single-cell gene expression (scRNA-seq of 39,263 cells) and chromatin accessibility applied to ten genetically-homogeneous, patient-derived melanoma cultures, to examine intra- and intertumoral phenotypic heterogeneity, to identify new cell states, and to track dynamic transitions at single-cell resolution.

ORGANISM(S): Homo sapiens

PROVIDER: GSE134432 | GEO | 2020/07/10

REPOSITORIES: GEO