Mapping Gata2 enhancer-dependent developmental trajectories by single-cell RNA-sequencing

ABSTRACT: We compared single-cell transcriptomes of fetal liver myeloid progenitor pools (CMP/GMP pool) from Gata2 -77 enhancer mutant embryos and wildtype littermates. Gene expression patterns in -77-deficient mice demonstrated loss of erythroid, megakaryocyte and granulocyte progenitors and an increase in monocyte

ORGANISM(S): Mus musculus

PROVIDER: GSE134439 | GEO | 2020/06/03

REPOSITORIES: GEO