Transcriptomics

Dataset Information

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Expression data of BCPAP cells with LRRC34 knockdown


ABSTRACT: A recent genome-wide association study (GWAS) in thyroid cancer discovered 3q26 as one of five loci implicated in thyroid cancer predisposition. The tag SNP, rs6793295, is located in exon 7 of LRRC34. However, there are genetically distinct, but population-specific signals upstream of LRRC34 that demonstrate allele-specific expression. In order to reveal the regulatory gene network of LRRC34 in thyroid cells, microarray analysis was performed in the BCPAP cell line treated with siRNA against LRRC34.

ORGANISM(S): Homo sapiens

PROVIDER: GSE134694 | GEO | 2019/12/31

REPOSITORIES: GEO

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