H2BG53D mutation in PDAC

ABSTRACT: Study was conducted to understand the effect of the cancer associated H2BG53D mutation in PDAC. Using CRISPR/Cas9 Knock-in cell lines expressing FLAG-tagged WT and G53D mutant H2B, we conducted gene expression profilling experiments and studied the effect of the H2BG53D mutation on transcription and PDAC development.

ORGANISM(S): Homo sapiens

PROVIDER: GSE134864 | GEO | 2020/07/01

REPOSITORIES: GEO