Genomics

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Transcriptomic analysis of Arthrobacter sp. CGMCC 3584 responding to pde gene knockout


ABSTRACT: Arthrobacter sp. CGMCC 3584 are able to produce high yields of extracellular cyclic adenosine monophosphate (cAMP), which plays a vital role in the field of treatment of disease and animal food, during aerobic fermentation. Comparative transcriptomic analysis revealed that arpde inactivation had two major effects on metabolism: inhibition of glycolysis, PP pathway, and amino acid metabolism; promotion of the purine metabolism and carbon flux from the precursor PRPP, which benefited cAMP production.

ORGANISM(S): Clostridium acetobutylicum Arthrobacter sp. CGMCC 3584 Arthrobacter sp.

PROVIDER: GSE134961 | GEO | 2020/01/01

REPOSITORIES: GEO

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