Transcriptomic analysis of Arthrobacter sp. CGMCC 3584 responding to pde gene knockout

ABSTRACT: Arthrobacter sp. CGMCC 3584 are able to produce high yields of extracellular cyclic adenosine monophosphate (cAMP), which plays a vital role in the field of treatment of disease and animal food, during aerobic fermentation. Comparative transcriptomic analysis revealed that arpde inactivation had two major effects on metabolism: inhibition of glycolysis, PP pathway, and amino acid metabolism; promotion of the purine metabolism and carbon flux from the precursor PRPP, which benefited cAMP production.

ORGANISM(S): Clostridium acetobutylicum Arthrobacter sp. CGMCC 3584 Arthrobacter sp.

PROVIDER: GSE134961 | GEO | 2020/01/01

REPOSITORIES: GEO