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RBMX preferentially associates with repetitive DNAs along with RPA

ABSTRACT: To characterize the binding sites of RBMX and RPA on chromatin, 293T cells were treated with CPT and binding profiles were obtained by ChIP-seq assay. RBMX ChIP-seq profile was highly correlated with RPA ChIP-seq profile, both showing strong peaks at centromeres. To characterize the occupancy sites bound by both RBMX and RPA, we annotated their shared peaks. The results showed that these sequences are mostly enriched on repetitive DNAs including rRNA, simple repeats and satellite DNAs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE134980 | GEO | 2019/07/27

REPOSITORIES: GEO

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RBMX preferentially associates with repetitive DNAs along with RPA

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