Human macrophage responses to viral-like particles from non-IBD or IBD colonic resections

ABSTRACT: Peripheral blood-derived macrophages were stimulated with viral-like particles isolated from colonic resections from patients with Crohn's disease (CD), ulcerative colitis (UC), or non-IBD controls diagnoses. RNAseq was performed to unbiasedly assess the transcriptional responses to these stimuli and revealed highly divergent macrophage transcriptional programs in response to non-IBD compared to IBD VLP.

ORGANISM(S): Homo sapiens

PROVIDER: GSE135223 | GEO | 2020/06/01

REPOSITORIES: GEO