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CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms

ABSTRACT: Exon Level Expression Profiling of HeLa cells depleted of DNMT1 by 2 independent siRNAs In HeLa cells where depletion of DNMT1 was sufficient to cause reduced levels of DNA methylation inside the body of CD44 and reduced usage of CD44 variant exons, without affecting splicing factors regulating CD44.

ORGANISM(S): Homo sapiens

PROVIDER: GSE135277 | GEO | 2021/05/10

REPOSITORIES: GEO

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CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms.

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CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms

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microRNA expression profiles in CD44- and CD44+ hepatocellular carcinoma HuH7 cells

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