Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress

ABSTRACT: Loss of Pggt1b leads to marked defects in thymocyte egress and T cell lymphopenia in peripheral lymphoid organs in vivo CD4SP thymocytes (n = 4 per genotype) were isolated from the thymus of WT and Pggt1b KO mice

ORGANISM(S): Mus musculus

PROVIDER: GSE135301 | GEO | 2019/11/04

REPOSITORIES: GEO