Genomics

Dataset Information

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OncoScan CNV SNP array data for MNG/PTC samples


ABSTRACT: Genome-wide copy number analysis using SNP-arrays (OncoScans) in multinodular goitres from individuals with the c.1552G>A;p.E518K mutation in DGCR8 show allelic imbalance at Chr22 in all samples. Likewise this event is confirmed in papillary thyroid tumors harboring the same alteration somatically. The only alteration common in all MNG and FvPTC samples was the allelic imbalance at the Chr22 in line with all samples showing an homozygous genotype at the DGCR8 locus

ORGANISM(S): Homo sapiens

PROVIDER: GSE135374 | GEO | 2019/11/01

REPOSITORIES: GEO

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