Genomics

Dataset Information

0

Zika Virus Noncoding sfRNA Sequesters Multiple RNA Binding Proteins and Impacts mRNA Decay and Splicing


ABSTRACT: Previous reports studying similar flavivirus infections (DENV, WNV, etc.) revealed an increase in both the abundance and stability of normally short-lived cellular mRNAs. This resulted from the stalling/repression of the major 5’-3’ host exoribonuclease XRN-1 on three-helix junction structures present in the 3’-UTR of insect-borne flaviviruses. Therefore we sought to identify the endogenous mRNA abundance and stability changes induced during early and late times following Zika virus infection (PRBRAC59) in human choriocarcinoma (JAR) cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE135413 | GEO | 2019/08/06

REPOSITORIES: GEO

Similar Datasets

2014-01-03 | E-GEOD-53784 | biostudies-arrayexpress
2017-11-29 | PXD008120 | Pride
2020-05-14 | PXD016805 | Pride
2014-01-03 | GSE53784 | GEO
2019-11-14 | PXD011728 | Pride
2021-12-25 | GSE192446 | GEO
2012-12-29 | E-GEOD-43190 | biostudies-arrayexpress
2020-02-24 | GSE133284 | GEO
2011-04-28 | E-MTAB-429 | biostudies-arrayexpress
2019-01-17 | GSE125241 | GEO