RNA-seq Analysis of the gene expression regulated by CID755673 in mouse embryonic stem cells

ABSTRACT: Purpose:The goals of this study is to analyze the candidate genes motified by CID755674 to promote the mouse embryonic stem cell (ESC) self-renewal through RNA-seq approach. Previously, we found that MEK inhbitior PD0323901 (PD) coporates with protein kinase D inhibitor CID755673 (CID) is able to maitain mouse embryonic stem cell (mESC) self-renewal, we named this conditon is "PC". In order to find out why CID755673 can promote mouse embryonic stem cell self-renewal, we performed RNA-sequence in mESCs treated with PD or PC, and tried to identify the key mechanisms under CID

ORGANISM(S): Mus musculus

PROVIDER: GSE135625 | GEO | 2019/08/10

REPOSITORIES: GEO