Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies

ABSTRACT: The objective of this study is to characterize the overall transcriptome of P. falciparum NF54 derived from a controlled-human malaria infection (CHMI) study. Healthy, immunologically naïve human volunteers were infected intradermally or intravenously with different dosages of Plasmodium falciparum sporozoites (Sanaria® PfSPZ Challenge). Parasites were isolated from these volunteers and subjected to a range of in vitro culture generation prior to RNA collection.

ORGANISM(S): Plasmodium falciparum 3D7 Plasmodium falciparum NF54 Plasmodium falciparum

PROVIDER: GSE136076 | GEO | 2019/08/21

REPOSITORIES: GEO