Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells

ABSTRACT: We report the differential gene expression in control versus ZC3H18-depleted OVCAR-8 cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE136533 | GEO | 2019/08/29

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

RNA-seq analysis of control and CDK12-depleted ovarian cancer cells

Project description:We report the differential gene expression in control versus CDK12-depleted OVCAR-8 cells

2019-10-03 | GSE138288 | GEO

RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells

Project description:RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells

| PRJNA562626 | ENA

Profiling of differential RNAs in alpha amanitin treated SORBS2-depleted ovarian cancer cells and control-treated SORBS2-depleted

Project description:In this study, we examined the differential RNA profile of alpha amanitin-treated SORBS2-depleted ovarian cancer cells compared with control-treated SORBS2-depleted cells

2018-02-20 | GSE101595 | GEO

Profiling of differential RNAs in SORBS2-depleted ovarian cancer cells and control cells

Project description:In this study, we examined the differential RNA profile of SORBS2-depleted ovarian cancer cells compared with control cells

2018-02-20 | GSE101594 | GEO

Transcriptional profiling of control versus PAF depleted mouse lung cancer cell lines

Project description:Transcriptional profiling of control versus PAF depleted mouse lung cancer cell lines

| PRJNA562707 | ENA

RNA-seq analysis of control and CDK12-depleted ovarian cancer cells

Project description:RNA-seq analysis of control and CDK12-depleted ovarian cancer cells

| PRJNA575346 | ENA

Isolation and characterization of stem-like cells from a human ovarian cancer cell line

Project description:Increasing evidence supports the existence of a subpopulation of cancer cells capable of self-renewal and differentiation into diverse cell lineages. These cancer stem-like or cancer initiating cells (CICs) also demonstrate resistance to chemo- and radiotherapy and may function as a primary source of cancer recurrence. We report here on the isolation and in vitro propagation of multicellular ovarian cancer spheroids from a well-established ovarian cancer cell line (OVCAR-3). Cells forming these spheroids display self-renewal potential, the ability to produce differentiated progeny and increased expression of genes previously associated with CICs. The spheroid-derived cells (SDCs) also demonstrate higher invasiveness, migration potential and enhanced resistance to standard anticancer agents relative to progenitor OVCAR-3 cells. SDCs display up-regulation of genes associated with epithelial-to-mesenchymal transitions (EMT), anticancer drug resistance and/or decreased susceptibility to apoptosis, as well as, down-regulation of genes typically associated with the epithelial cell phenotype and pro-apoptotic genes. Dataset includes 3 replicate cultures of parental OVCAR-3 cells and 3 replicate cultures of stem cell-like spheroid-derived cells

2011-04-23 | E-GEOD-28799 | biostudies-arrayexpress

An experimental model for ovarian cancer: Propagation of ovarian cancer initiating cells and generation of ovarian cancer organoids

Project description:To establish an iOCIC model, an high-grade serous ovarian cancer (HGSOC) cell line, OVCAR-3 was reprogrammed by transducing Yamanaka four factors OCT4, SOX2, KLF4 and MYC (OSKM) We then performed gene expression profiling analysis using data obtained from RNA-seq of 3 different cells.

2022-09-20 | GSE201206 | GEO

Gene expression profiling of N-acetylglucosaminidase (NAGLU)-depleted HeLa cells versus non-depleted cells

Project description:We generated a HeLa cell model of mucopolysaccharidosis IIIB (MPSIIIB) by depleting NAGLU. MPSIIIB-associated cell defects were prominent in NAGLU-depleted cells. We explored alterations of metabolic pathways in NAGLU-depleted cells versus non-depleted control cells by performing gene expression profiling. Exon array transcriptome analysis showed 96 transcripts with increased expression level and 38 transcripts with decreased expression level in NAGLU-depleted versus non-depleted cells.

2012-09-13 | GSE32154 | GEO

Transcriptional profiling of control versus PAF depleted human lung cancer cell line (H1792)

Project description:Transcriptional profiling of control versus PAF depleted human lung cancer cell line (H1792)

| PRJNA613709 | ENA