Genome-wide RNA sequencing on myeloid derived suppressor cells from mice treated with lymphodepleting chemotherapy

ABSTRACT: Myeloid derived suppressor cells (MDSCs) were sorted from B16 tumor-bearing mice that were untreated or given lymphodepleting cyclophosphamide and fludarbine. We report that monocytic and polymorphonuclear MDSC subsets (M-MDSCs and PMN-MDSCs respectively) have a unique gene expression profile in comparison to MDSCs collected from untreated tumor-bearing animals.

ORGANISM(S): Mus musculus

PROVIDER: GSE136574 | GEO | 2020/07/03

REPOSITORIES: GEO