RNA-seq analysis of WT and CARD11 point mutation mouse spleen B cells

ABSTRACT: In order to investigate the molecular mechanism of CARD11 in immune cell system, we applied the RNA-seq analysis using RNA isolated from WT and CARD11 mutant (E134G and K215M) mouse spleen B cells. By comparing the transcriptome files, we found some different expressed gene involved in due to the CARD11 point mutation and in vitro RT-PCR had confirmed this result.

ORGANISM(S): Mus musculus

PROVIDER: GSE136588 | GEO | 2020/01/27

REPOSITORIES: GEO