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Intestinal tumor expression data from Apcmin/+ mice gavaged by feces from healthy controls or colorectal cancer patients

ABSTRACT: Colorectal cancer (CRC) is closely related to gut dysbiosis. We investigated the effects of imbalanced gut microbiota on the progression of intestinal adenoma in Apcmin/+ mice model using fecal microbiota transplantation (FMT). Administration of feces from CRC patients increased tumor proliferation and decreased apoptosis in tumor cells. Abnormal expression of genes related to Wnt-protein binding and lipid metabolic process was observed.

ORGANISM(S): Mus musculus

PROVIDER: GSE136682 | GEO | 2019/09/16

REPOSITORIES: GEO

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Impact of fecal microbiota transplantation (FMT) in 3 days-ABX-treated recipient mice using feces from 6 NSCLC patients at diagnosis.

Project description:This study aimed to analyze changes in gut microbiota composition in mice after transplantation of fecal microbiota (FMT, N = 6) from the feces of NSCLC patients by analyzing fecal content using 16S rRNA sequencing, 10 days after transplantation. Specific-pathogen-free (SPF) mice were used for each experiments (N=4) as controls.

2023-07-01 | E-MTAB-12812 | biostudies-arrayexpress

16S rRNA gene sequence analysis of feces samples from rats treated with paclitaxel or vehicle controls

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The effects of obesity microbiota produced metabolites on colorectal carcinogenesis in murine models

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2022-05-18 | ST002193 | MetabolomicsWorkbench

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The impact of gut microbiome on transcriptome in Parkinson's disease model revealed by fecal microbiota transplantation

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2019-05-08 | E-MTAB-7750 | biostudies-arrayexpress

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