Plant toxin treatment of neonatal mouse cholangiocytes

ABSTRACT: Extrahepatic bile ducts were isolated from mouse pups at days 0-3 and primary cholangiocytes were isolated. Cholangiocytes were treated with DMSO, bilatresone (TOX4), betavulgarin (TOX2), and isoflavanone (TOX3), as per Lorent et al, Science Translationa Medicine 2015;286:286ra67 (Fig. 1), all in DMSO. Treatment concentrations were 2.0 micrograms/ml, for 6 hours.

ORGANISM(S): Mus musculus

PROVIDER: GSE136895 | GEO | 2020/01/01

REPOSITORIES: GEO