Differential gene expression during embryoid body (EB) formation of mouse embryonic stem cells when Hnrnpll was depleted

ABSTRACT: This work indicates Hnrnpll depletion mES cells cannot exit from pluripotency programme, showing embryoid body formation deficiency and no spontaneous differentiation withdraw LIF. Hnrnpll promotes multiple ES cell preferred-exon skipping during ES cells differentiation, to reduce the ES cells specific isoform and facilitate ES cells exit from pluripotency towards differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE136955 | GEO | 2020/12/06

REPOSITORIES: GEO