Profiling open chromatin regions in human myometrial tissues

ABSTRACT: The open chromatin regions of nonpregnant and term pregnant human myometrial tissues were assessed by ATAC-seq to gain insight on potential genome regulatory elements in vivo. patterns of accessible genome change between NP and TP myometrium, leading to altered enrichment of binding motifs for hormone and muscle regulators such as the progesterone receptor (PGR), Krüppel-like factors and MEF2A transcription factors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE137549 | GEO | 2019/11/28

REPOSITORIES: GEO