MiRNA-Mediated Suppression of a Cardioprotective Cardiokine as a Novel Mechanism Exacerbating Post-MI Remodeling by Sleep Breathing Disorders [RNA-Seq]

ABSTRACT: This study provides the first evidence that MI+CIH upregulates miR-214-3p, suppresses cardiac CTRP9 expression, and exacerbates cardiac remodeling, suggesting that CTRP9 may be a novel therapeutic target against pathologic remodeling in MI patients with OSA

ORGANISM(S): Mus musculus

PROVIDER: GSE138008 | GEO | 2019/09/25

REPOSITORIES: GEO