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Potentiating the activity of berberine for Staphylococcus aureus in a combinatorial treatment with thymol

ABSTRACT: In the current study, RNA sequencing based transcriptional profiling was used to elaborate the combinatorial effect of berberine, a well-known antibacterial alkaloid, and thymol, a monoterpenic phenol, on the Staphylococcus aureus transcriptome.

ORGANISM(S): Staphylococcus aureus

PROVIDER: GSE138090 | GEO | 2020/10/09

REPOSITORIES: GEO

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An OMIC approach to elaborate the antibacterial mechanisms of different alkaloids

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Potentiating the activity of berberine for Staphylococcus aureus in a combinatorial treatment with thymol

Project description:Potentiating the activity of berberine for Staphylococcus aureus in a combinatorial treatment with thymol

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MicroRNA expression profiling of primary human hepatocytes after berberine chloride treatment

Project description:Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Since xenobiotic drug-induced micoRNAs have recently emerged as key regulators in guiding their pharmacological effects and toxicity, we were interested in whether or not micoRNA expression was differentially altered by berberine treatment in liver. Here, we used miRNA microarray to analyze microRNA expression profiles of primary human hepatocytes after berberine chloride treatment or 0.08% DMSO as control. Comparing miRNA profiles of 40 ïM berberine-treated primary human hepatocytes to those of control cells sampled after 2 hours treatment. A 50 mM stock solution of Berberine chloride was prepared in DMSO. Cells were treated with 40 ïM berberine chloride or 0.08% DMSO as control.

2015-12-31 | E-GEOD-53413 | biostudies-arrayexpress

Genome-wide analysis of berberine chloride-responsive gene expression in HepG2 liver cell line

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Genome-wide analysis of berberine chloride-responsive gene expression in HepG2 liver cell line

Project description:Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Here, we used gene expression microarray to analyze gene expression profiles of HepG2 human hepatoma cell line after berberine chloride treatment or 0.08% DMSO as control. Comparing gene expression profiles of 40 M-BM-5M-BM--M berberine-treated HepG2 human hepatoma cell line to those of control cells sampled after 4 hours treatment. A 50 mM stock solution of Berberine chloride was prepared in DMSO. Cells were treated with 40 M-BM-5M-BM--M berberine chloride or 0.08% DMSO as control.

2013-10-02 | E-GEOD-47786 | biostudies-arrayexpress

Gene expression profiling of primary human hepatocytes after berberine chloride treatment

Project description:Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Since xenobiotic drug-induced micoRNAs have recently emerged as key regulators in guiding their pharmacological effects and toxicity, we were interested in whether or not micoRNA expression was differentially altered by berberine treatment in liver. Here, we used miRNA microarray to analyze microRNA expression profiles of primary human hepatocytes after berberine chloride treatment or 0.08% DMSO as control. Comparing gene expression profiles of 40 ï?M berberine-treated primary human hepatocytes to those of control cells sampled after 2, 4, or 8 hours treatment. A 50 mM stock solution of Berberine chloride was prepared in DMSO. Cells were treated with 40 ï?M berberine chloride or 0.08% DMSO as control.

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Gene expression profiling of primary human hepatocytes after berberine chloride treatment

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2015-12-31 | GSE53413 | GEO

MicroRNA expression profiling of HepG2 liver cells after berberine chloride treatment

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