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Genome-wide screening of N6-methyladenosine modification pattern in clear cell renal cell carcinoma (ccRCC)

ABSTRACT: m6A modification patterns in ccRCC and normal tissues were described via m6A-sequencing and RNA-sequencing, followed by bioinformatics analysis. m6A-related RNAs were immunoprecipitated by anti-m6A antibody-coupled beads, and validated by qPCR.

ORGANISM(S): Homo sapiens

PROVIDER: GSE138274 | GEO | 2019/12/27

REPOSITORIES: GEO

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Structure and Thermodynamics of N6-methyladenosine in RNA: a Spring-Loaded Base Modification

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Genome-wide screening of N6-methyladenosine modification pattern in clear cell renal cell carcinoma (ccRCC)

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Project description:N6-methyladenosine (m6A) is one of the most popular RNA modifications, which is widely found in messenger RNAs (mRNAs) and non-coding RNA like long no-coding RNA (lncRNAs) and circular RNA (circRNAs).In our study,we provide m6A landscape of human ameloblastoma, which expands the understanding of m6A modifications and uncovers regulation of lncRNAs and circRNAs through m6A modification in ameloblastoma.

2020-10-08 | GSE156886 | GEO

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