An in vivo CRISPR screen identifies stepwise genetic dependencies of metastatic progression

ABSTRACT: In vivo genome-wide loss-of-function CRISPR screen identifies critical genes required for individual steps of the metastatic cascade in human CTC-derived xenografts, suggesting novel drivers and vulnerabilities of breast cancer metastasis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE138813 | GEO | 2022/01/27

REPOSITORIES: GEO