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Phospho-antibody microarray analyses for islets of control and IFT88 knockout mice [PEX100]

ABSTRACT: β-cell specific IFT88 knock-out mice recapitulate human diabetes with impaired insulin secretion and altered islet hormone paracrine regulation. To examine the signaling pathways regulating islet cell function, we subjected protein lysates of whole islets from control and IFT88 knockout mice to a commercial phospho-antibody array analysis (Full Moon Bio, Inc). Samples were probed against 1318 site-specific and phospho-specific antibodies with 2 replicates per antibody on 76 x 25 x 1mm glass slides.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE138856 | GEO | 2019/10/30

REPOSITORIES: GEO

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