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H3K79me2 and H3K4me3 in CD8 T cell subsets

ABSTRACT: We studied the role of the histone methyltransferase DOT1L in T cell development and differentiation. H3K79me2 and H3K4me3 ChIP-sequencing data was generated from sorted CD8 single positive thymocytes, naïve CD8 splenocytes and memory CD8 splenocytes. This was compared to RNA-sequencing data from WT and Dot1L KO mice in order to study the link between H3K79me2 and transcription.

ORGANISM(S): Mus musculus

PROVIDER: GSE138908 | GEO | 2020/07/29

REPOSITORIES: GEO

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