Profiling the effect of Nafcillin on HA-MRSA D712 using bacteriological and physiological media

ABSTRACT: Vancomycin Intermediate Staphylococcus aureus (VISA) strain originated during the prolonged hospitalization, chronic infection and vancomycin treatment. The hospital acquired D712 VISA strain were subjected to various sub-inhibitory concentration of nafcillin in Cation Adjusted Mueller Hinton Broth (CA-MHB) and Roswell Park Memorial Institute (RPMI) medium. The MIC of has dropped from 256 ug/ml to 1ug/ml in CA-MHB and RPMI media respectively. The cells were harvested and expression profiling were measured using RNA sequencing at time point of 03 hours.

ORGANISM(S): Staphylococcus aureus

PROVIDER: GSE139141 | GEO | 2019/10/22

REPOSITORIES: GEO