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Quercetin attenuates atherosclerosis via modulating oxidized LDL-induced endothelial cellular senescence

ABSTRACT: We have employed transcriptome microarray expression profiling as a discovery platform to figure out the pharmacological mechanisms of quercetin against endothelial senescence induced by ox-LDL in vitro. Expression of RCHY1, EIF4E1B, IGFBP3, SERPINE1, BRAF, SLC5A11 from this signature was quantified in the same kind of samples by real-time PCR, confirming the change pattern.

ORGANISM(S): Homo sapiens

PROVIDER: GSE139288 | GEO | 2019/10/29

REPOSITORIES: GEO

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High-throughput Sequencing Facilitates Quantitative Analysis of Transcriptome Difference Underlying Quercetin Antioxidant Action in Ox-LDL-induced HUVECs Damage [ncRNA-Seq]

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Quercetin attenuates atherosclerosis via modulating oxidized LDL-induced endothelial cellular senescence

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Expression data from ARPE-19 cells treated with LDL or ox-LDL

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