RNA-seq profiles of reprogramming cells at Day 3 and Day 6 from MEFs to iPS cells [siNcor1 or siOct4]

ABSTRACT: AIM: To detect differences in transcriptional profiles after knocking down Ncor1 or Oct4, compared to a negative control in early reprogramming to pluripotency. DESCRIPTION: RNA-seq profiles of early reprogramming mouse embryonic fibroblasts (MEFs) transduced with lentivirus containing doxycycline-inducible OSKM factors to induce pluripotency . Before starting reprogramming, OSKM-MEFs were transfected with different siRNAs and then they were reprogrammed for 3 or 6 days.

ORGANISM(S): Mus musculus

PROVIDER: GSE139376 | GEO | 2020/03/27

REPOSITORIES: GEO