CRISPRi proliferation dropout screen of EGFR cis-regulatory elements

ABSTRACT: Here we have used using a pooled proliferation dropout screen with KRAB-dCas9 to determine the contribution of cis-regulatory elements around EGFR to cell fitness in EGFR unamplified (GSC23) and amplified (GBM3565) glioblastoma .

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE139415 | GEO | 2019/11/25

REPOSITORIES: GEO