MiRNA microarray in the synovial tissue 14 days after anterior cruciate ligament transection (ACLT)

ABSTRACT: To investigate changes in miRNA expression in the synovial tissue, miRNA microarray was performed at day 14 after ACLT and revealed that several miRNA expressions were changed more than 1.5-fold. We chose to analyze the role of miR-21 in joint pain after ACLT because it had the highest signal intensity among the increased miRNAs. Quantitative PCR confirmed that miR-21 expression in synovial tissue was significantly increased 14 days after ACLT.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE139532 | GEO | 2019/10/30

REPOSITORIES: GEO