Post-translational regulation of the exon skipping machinery controls aberrant splicing in T cell leukemia [Jurkat_shSRSF6]

ABSTRACT: In this study, we show that pediatric T-cell acute lymphoblastic leukemia (T-ALL) has an alternative mechanism for aberrant splicing that involves post-translational regulation of the splicing machinery via deubiquitination.

ORGANISM(S): Homo sapiens

PROVIDER: GSE139621 | GEO | 2020/06/01

REPOSITORIES: GEO