Single-cell transcriptomic analysis of human germinal center B cells

ABSTRACT: In response to T cell-dependent antigens, mature B cells are stimulated to form germinal centers, which are the place of B cell affinity maturation and selection. Here, we dissected the heterogeneity of germinal center B cells and reconstructed their pathway of differentiation using single-cell transcriptomic analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE139891 | GEO | 2020/06/17

REPOSITORIES: GEO