SOCS3 deficiency blocked autophagy-dependent myeloid differentiation of early-stage myeloid-derived suppressor cells via the miR-155/C/EBPβ/Wnt axis

ABSTRACT: To explore which pathways participated in dysfunctional eMDSC differentiation, we performed RNA sequencing on Gr-1 cells, eMDSCsfl/fl and eMDSCsKO to screen for potential candidates that might participate in the SOCS3-deficiency-induced differentiation arrest in eMDSCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE140092 | GEO | 2022/10/31

REPOSITORIES: GEO