Habenular Tcf7l2 links nicotine addiction to diabetes.

ABSTRACT: Translational profiling of cholinergic neurons in the MHb allow identification of genes that are responsive to metabolic changes. Here we use bac TRAP to access translating mRNAs. We confirm a role for the transcription factor Tcf7l2 in the MHb in both glucose homeostasis and nicotine intake.

ORGANISM(S): Mus musculus

PROVIDER: GSE140142 | GEO | 2019/11/09

REPOSITORIES: GEO