Abrogation of esophageal carcinoma development by miR-31 genetic knockout

ABSTRACT: Transcriptomics analyses in these Zn-deficient rats revealed the molecular basis of ESCC abrogation by miR-31 knockout: Egln3, a negative regulator of NF-FB, was shown to be a direct miR-31 target; miR-31 inhibition/deletion resulted in suppression of miR-31-associated-EGLN3-NF-KB controlled inflammatory pathways.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE140190 | GEO | 2020/03/30

REPOSITORIES: GEO