ASK1 Inhibition Reduces Cell Death and Hepatic Fibrosis in an Nlrp3 Mutant Liver Injury Model

ABSTRACT: The aim of the current study was to investigate whether pharmacologic inhibition of ASK1 could attenuate hepatic fibrosis driven by inflammasome activation using gain-of-function NOD-like receptor protein 3 (Nlrp3) mutant mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE140742 | GEO | 2020/02/01

REPOSITORIES: GEO