RNA Transcriptome of Tregs in Idiopathic Aplastic Anemia

ABSTRACT: Our report demonstrates that the dominant Treg population in AA are FasL resistant but do not respond to low concentration of IL-2, leading to immune dysregulation. And In vitro expanded AA Tregs are stable, functional and highly express p-BCL-2 with therapeutic potential in AA patients

ORGANISM(S): Homo sapiens

PROVIDER: GSE140844 | GEO | 2020/10/07

REPOSITORIES: GEO