Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single Cell Transcriptomics identifies Focal Segmental Glomerulosclerosis Remission Endothelial Biomarker

ABSTRACT: Intrinsic nephron cell types and tissue resident immune cells were recovered from renal biopsy specimens using a scRNAseq protocol for the Kidney Precision Medicine Project (KPMP), designed for deployment in a multicenter research network. Combined processing of 24 samples including 16 tumor-nephrectomy, 5 surveillance and 3 pre-perfusion biopsies using the scRNAseq protocol yielded 22,268 cells (4690 from surveillance biopsies, 16,491 from tumor-nephrectomies and 2834 cells from pre-perfusion biopsies) .

ORGANISM(S): Homo sapiens

PROVIDER: GSE140989 | GEO | 2020/03/03

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Exon Level Expression Profiling of focal segmental glomerulosclerosis

Project description:Transcriptome comparison of glomeruli from kidneys with focal segmental glomerulosclerosis (FSGS) and glomeruli from the unaffected portion of tumor nephrectomies. High-density Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used for the gene expression analysis.

2018-10-16 | GSE121233 | GEO

Exon Level Expression Profiling of Focal Segmental glomerulosclerosis (FSGS)

Project description:Transcriptome comparison of glomeruli from kidneys with FSGS and glomeruli from the unaffected portion of tumor nephrectomies. This study aims to investigate the pathogenesis and the mechanism of FSGS

2019-05-03 | GSE129973 | GEO

Transcriptome analysis of tubular tissues of focal segmental glomerulosclerosis patients

Project description:Transcriptome comparison of tubular tissues from kidneys with focal segmental glomerulosclerosis (FSGS) and tubular tissues from the unaffected portion of tumor nephrectomies. High-density Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used for the gene expression analysis.

2018-10-15 | GSE121211 | GEO

Transcriptome analysis of tubulointerstitial tissues of patients with focal segmental glomerulosclerosis

Project description:Transcriptome comparison of tubulointerstitial tissues from kidneys with focal segmental glomerulosclerosis (FSGS) and tubulointerstitial tissues from the unaffected portion of surgical nephrectomies. High-density Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used for the gene expression analysis.

2019-01-29 | GSE125779 | GEO

Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker.

Project description: Not available

| S-EPMC7213795 | biostudies-literature

An Outcomes-Based Definition of Proteinuria Remission in Focal Segmental Glomerulosclerosis.

Project description: Not available

| S-EPMC5967666 | biostudies-literature

A Molecular signature for Delayed Graft Function [BS-Seq]

Project description:Purpose: The aim of this study was to identify a molecular signature for extreme DGF in a retrospective analysis of paired renal allograft biopsies obtained at two time points: pre-implantation during preparatory phase (pre-perfusion biopsies, b) and after reperfusion when circulation was restored (post-perfusion biopsies , b1).

2019-01-18 | GSE90863 | GEO

A Molecular signature for Delayed Graft Function [RNA-Seq]

2019-01-18 | GSE90861 | GEO