The expression landscape of hepatocarcinogeneis in a rat model

ABSTRACT: Hepatocellular carcinoma (HCC) initiation is characterized by the sequential stepwise accumulation of molecular alterations. However, the earliest events during the dynamic temporal trend of hepatocarcinogenesis are still unknown. Using a diethylnitrosamine (DEN)-induced rat HCC model, we report a comprehensive transcriptomic landscape of liver tissues at the stages of hepatitis, cirrhosis, and HCC.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE141090 | GEO | 2020/11/10

REPOSITORIES: GEO