Expression data from control-knockout (CTR-KO) and MIF-KO human multiple myeloma (MM) cells

ABSTRACT: Macophage migration inhibitor (MIF) is important for MM resistance to proteasome inhibitors. To determine what signalling pathways are affected by MIF in MM cells, we established MIF-KO MM.1S and ARP-1 MM cell lines. Total RNAs of 2 x 106 CTR-KO and MIF-KO MM cells were extracted by RNeasy Mini Kit (Qiagen). 5-10 µg RNA samples were sent to Gene Expression and Genotyping Facility at Case Western Reserve University (Cleveland, OH) for RNA-seq followed by data analysis. We use microarray data to determine differential expression of genes in MIF-KO and CTR-KO MM cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE141170 | GEO | 2020/05/07

REPOSITORIES: GEO