Transcriptomic analysis of the effect of iron overload in human iPSC-CMs

ABSTRACT: We used human iPSC-CMs generated from healthy individuals and performed RNA-sequencing after 5 days of trastuzumab treatment to examine the mechanism associated with cardiac dysfunction in iPSC-CMs after iron treatment. Transcriptome analysis revealed broad changes in cardiovascular development and processes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE141678 | GEO | 2020/06/08

REPOSITORIES: GEO