IsoCirc catalogs full-length circular RNA isoforms in human transcriptomes

ABSTRACT: We report isoCirc, a long-read sequencing strategy coupled with an integrated computational pipeline to characterize full-length circular RNA (circRNA isoforms) using rolling circle amplification (RCA) followed by long-read sequencing. Applying isoCirc to 12 human tissues, we determined full-length structures and examined tissue specificities of circRNA isoforms in human transcriptomes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE141693 | GEO | 2020/09/12

REPOSITORIES: GEO