Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes

ABSTRACT: The gene expression patterns of astrocyte harboring active vs restricted LTRs were similar, and that the active population demonstrated more widespread and robust changes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE141756 | GEO | 2019/12/18

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes

Project description:Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes

| PRJNA594628 | ENA

RNA-Seq of human astrocytes

Project description:Astrocytes were purified from fetal and adult human brain tissue using an immunopanning method with the HepaCAM antibody. Samples were taken from otherwise 'healthy' pieces of tissue, unless otherwise specified. 6 fetal astrocyte samples, 12 adult astrocyte samples, 8 GBM or sclerotic hippocampal samples, 4 whole human cortex samples, 4 adult mouse astrocyte samples, and 11 human samples of other purified CNS cell types

2015-12-11 | E-GEOD-73721 | biostudies-arrayexpress

Dexamethasone regulation of mRNAs in astrocytes in vitro

Project description:Analysis of mRNA gene expression changes mediated by synthetic GR-agonist dexamethasone in mouse cortical primary astrocyte cultures Total RNA obtained from astrocyte cultures subjected to 0.25, 1, 2, 4, 6, 12, 18, or 24 hours of ~100nM dexamethasone exposure compared to vehicle control astrocyte cultures

2014-06-25 | E-GEOD-39272 | biostudies-arrayexpress

Identification of HLA-B*57:01-restricted endogenous and HIV epitopes

Project description:A novel modified HLA-B*57:01-restricted epitope was identified in one of the reversed-phase fractions following immunoaffinity purification of HLA-peptide complexes from C1R cells expressing HIV envelope protein. Also includes six immunopeptidome datasets from several B57 and env transfected cell lysates.

2018-02-19 | PXD004471 | Pride

Chemical conversion of human fetal astrocytes into neurons through modulation of multiple signaling pathways

Project description:To characterize the transcriptome of our cultured human astrocyte cell line, RNA-seq was performed and the data were compared with other available datasets.

2019-03-28 | GSE123397 | GEO

Maternal circulating microRNAs altered in fetal growth restricted pregnancies

Project description:Maternal circulating microRNAs altered in fetal growth restricted pregnancies

| PRJNA777894 | ENA

Comparison between calorie-restricted and time-restricted without calorie restriction

Project description:Comparison between calorie-restricted and time-restricted without calorie restriction

| PRJNA706697 | ENA

Analysis of global gene expression in fetal astrocytes and pluripotent stem cell derived neural stem cells

Project description:Gene expression was compared between two sets of commercially obtained fetal astrocytes and two sets of neuronal stem cell lines derived from iPSC and ES cells. Pathways and genes critical for astrocyte development and maintenance were identified in the analysis. Total RNA obtained from fetal astrocytes from two sources compared to total RNA obtained from two neuronal stem cell lines.

2014-02-02 | E-GEOD-53404 | biostudies-arrayexpress

Transcriptome analysis of senescent and reactive human fetal astrocytes

Project description:Senescence was recently linked to neurodegeneration. Senescent as well as reactive astrocytes were detected in Parkinson’s disease postmortem brains. This study aimed to determine differences and similarities between senescent and reactive astrocytes. Astrocytes were treated with the stressors hydrogen peroxide or rotenone to induce senescence or with the cytokines TNFa+IL1a or with IL1b to induce reactivity in astrocytes. Comparing the transcriptome of senescent and reactive astrocytes revealed a set of genes specific to senescent astrocytes together with genes regulated in a similar way in both astrocyte states.

2021-06-09 | GSE126750 | GEO

Insights into the Gene Expression Profiles of Active and Restricted Red/Green-HIV+ Human Astrocytes: Implications for Shock or Lock Therapies in the Brain.

Project description: Not available

| S-EPMC7158706 | biostudies-literature