Influence of glycine betaine on the transcriptional profile of the Bacillus subtilis SigB regulon

ABSTRACT: To investigate whether salt-stress dependent activation of SigB is mitigated when cells are pre-loaded with the compatible solute glycine betaine, we analyzed salt induction of the SigB regulon in the presence of the precursor choline at a genome-wide level. The median expression value of SigB-regulated genes was 1.7-fold higher in cells that received choline immediately before salt stress compared to cells where choline was added 60 minutes prior to the salt stress.

ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 Bacillus subtilis

PROVIDER: GSE141882 | GEO | 2020/03/01

REPOSITORIES: GEO