RNA sequencing of the left ventricle from non-failing donors and heart failure samples from the MAGNet consortium

ABSTRACT: The Myocardial Applied Genomics Network (MAGNet; www.med.upenn.edu/magnet), collects and banks human cardiac tissue for genomic research. All subjects or next of kin provided written informed consent for tissue donation and analyses and all study protocols were approved by relevant institutional review boards. Left ventricular free-wall tissue was harvested at the time of cardiac surgery from subjects with heart failure undergoing transplantation and from unused donor hearts with apparently normal function. The heart was perfused with cold cardioplegia prior to cardiectomy to arrest contraction and prevent ischemic damage, and tissue specimens were frozen in liquid nitrogen.

ORGANISM(S): Homo sapiens

PROVIDER: GSE141910 | GEO | 2019/12/13

REPOSITORIES: GEO