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Gene expression profile of liver obtained from liver-specific LPIAT1 KO (LKO) mice on chow or high fat diet (HFD).

ABSTRACT: To investigate gene expression changes induced by LPIAT1 depletion, Lpiat1F/F and LKO mice were fed high fat diet (HFD) or chow for 18 weeks from 6 weels old and microarray gene profiling were performed. Categorization of the differentially expressed genes between HFD-fed Lpiat1f/f and LKO mice, in relation to their functions in biological pathways, revealed an enrichment of genes involved in inflammation and fibrosis

ORGANISM(S): Mus musculus

PROVIDER: GSE141920 | GEO | 2019/12/13

REPOSITORIES: GEO

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